How Oxyntra Reshapes the Rumen

A cascade from a single beneficial bacterium to better fiber digestion, higher milk fat, improved efficiency, and stronger disease resistance.

Rumen Ecosystem Science

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Foundation
Oxyntra Alters the Rumen Ecosystem

Potassium Carbonate Sesquihydrate and Magnesium Chelate shift the microbial balance โ€” crowding out bacteria that depress milk fat and efficiency, and creating conditions where beneficial bacteria thrive.

Potassium Carbonate SesquihydrateMagnesium ChelateFed at ~1% of DMI
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Key Microbe
Prevotella โ€” The Underappreciated Workhorse

Oxyntra selectively enriches Prevotella, a beneficial rumen bacterium that converts degradable protein into branched-chain amino acids (BCAAs) and transforms them into IsoValerate โ€” the fuel that activates the rumen's fiber-digesting workforce.

Degradable protein โ†’ BCAAsBCAAs โ†’ IsoValerate
๐Ÿ“„ Research: Supplementation in Lactating Dairy Cows โ†’
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Fiber Digestion Cascade
IsoValerate Activates Four Fiber-Digesting Bacteria

IsoValerate is a critical growth factor for the rumen's most powerful cellulolytic species โ€” dramatically increasing NDF and ADF digestibility and capturing more dietary carbon as usable energy rather than methane or manure.

ROD-SHAPED ยท GRAM-NEGATIVE
Fibrobacter succinogenes
Primary cellulose degrader; greatest cellulose digestion capacity of any rumen bacterium
COCCI ยท GRAM-POSITIVE
Ruminococcus albus
Highly cellulolytic; ferments cellulose to acetate and ethanol; major fiber degrader
COCCI ยท CELLULOSOME PRODUCER
Ruminococcus flavefaciens
Produces cellulosomes; high activity against crystalline cellulose; major NDF digestibility driver
CURVED ROD ยท FLAGELLATED
Butyrivibrio fibrisolvens
High butyrate producer; corrects biohydrogenation pathway; unique surface knobs for cell adhesion
๐Ÿ“„ Research: Mechanisms & Production Responses
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Production Outcomes
Increased Butyrate Drives Performance Gains

Improved fiber and carbohydrate digestibility shifts the VFA profile toward more acetate and significantly higher butyrate โ€” the key signal for milk fat synthesis, bacterial yield, and feed efficiency.

5%
Improvement in feed efficiency
15โ€“30%
Higher butyrate vs. baseline
โ†‘ Protein
Higher bacterial yield โ†’ more milk protein
โ†‘ Add More
High-linoleic oilseeds
Expellers / canola meal
Distillers grains
โ†“ Reduce / Remove
Bypass fat
Synthetic amino acids
Yeasts & DFMs
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Disease Resistance
Butyrate + Magnesium Chelate Activate Antioxidant Defense

Increased butyrate, supported by Magnesium Chelate, directly stimulates the cell's most powerful antioxidant enzyme complexes โ€” addressing oxidative stress, the hidden driver of mastitis, leaky gut, poor reproductive performance, and other morbidities.

Superoxide Dismutase (SOD)
First-line defense; neutralizes superoxide free radicals
Glutathione Peroxidase (GPx)
Eliminates peroxides; key mammary gland protector
Catalase (CAT)
Breaks down hydrogen peroxide in liver and blood
Nrf2-ARE Network
Master regulator; activates all phase II detox enzymes
Mastitis
Leaky gut
Reproductive failure
Lameness
Transition stress
High SCC
๐Ÿ“„ Research: Eliminating Inflammation โ€” Hoof Health
Net Cost Savings โ€” Wisconsin Farm Data (06/02/2026)
$0.46
per cow, per day
After removing bypass fat, synthetic amino acids, yeasts & DFMs from the ration

See what Oxyntra can do for your herd

Use our calculator to estimate your farm's savings and ROI.

Calculate My Savings โ†’

The next generation of dairy nutrition is here.