The Butyrate Advantage

By Scott Boken, M.S., and Fernando Valdez, Ph.D.

Overview

Oxyntra from Kalium Agri is a next-generation supplement designed to reduce oxidative stress (OS) and improve cow health from the inside out. By stimulating butyrate production and delivering chelated magnesium for superior absorption, Oxyntra addresses the underlying biological causes of inflammation, metabolic imbalance, and disease.

Butyrate strengthens gut and cellular barriers while preventing cell damage, and magnesium supports antioxidant enzyme systems and immune response. Together, they create a synergistic defense that improves animal health, productivity, and longevity across the herd.

Health Conditions: Incidence & Oxyntra Improvements

Oxyntra’s dual-action approach combats oxidative stress and enhances recovery across multiple systems, leading to fewer health issues and stronger performance outcomes.

Table 1: OS-Driven Health Problems & Oxyntra Benefits

Oxyntra Data Table
Condition Problem Description Incidence with OS (%) OxyNtra Improvement Key Data & Insights
Mastitis OS weakens udder defenses, leading to infections and inflammation. 20–40 (clinical) 10–25% lower incidence Butyrate reduces NF-κB cytokines; Mg lowers SCC 10–20%.
Ketosis OS disrupts energy metabolism, causing liver fat buildup. 15–30 (clinical/SCK 19–44) 10–20% fewer cases Butyrate improves energy use; Mg prevents hypomagnesemia (reduces ketosis 8–15%).
Hemorrhagic Bowel Syndrome (HBS) OS damages gut lining, causing bleeding and obstruction. 2–10 in affected herds 10–15% lower risk Butyrate + Mg strengthen gut barrier, reducing gut issues 20–30%.
Leaky Gut OS increases gut permeability, allowing toxins and inflammation. 10–20 yield loss (heat-related) 20–30% less permeability Butyrate supports tight junctions; Mg aids barrier integrity.
Low Conception Rates OS harms eggs and sperm, reducing fertility and embryo success. 20–30 drop (stressed cows) 10–15% higher conception Butyrate + Mg improve hormone balance; fertility +10–15%.

Digestibility & Production: Oxyntra’s Impact on Performance

Without proper rumen function, cows waste feed energy, produce more methane, and lose valuable yield potential. Oxyntra, powered by potassium carbonate sesquihydrate (KCS), boosts butyrate levels and fiber digestion, improving both animal health and production efficiency.

Table 2: Digestibility Challenges vs. Oxyntra Improvements

Oxyntra Performance Data
Area Problem Without Oxyntra Oxyntra Improvement (Data) Key Benefits
Fiber Digestibility Poor breakdown (5–10% lower DM/NDF/ADF); wasted feed and higher costs. +0.76% DMd, +1.17% NDFd, +1.47% ADFd (per 100 mEq DCAD). Better nutrient use, +5–12% efficiency.
Butyrate Production Lower levels (10–20% less) weaken gut and mammary cells. +0.58% butyrate (shifts VFA toward acetate/butyrate). Stronger cell health, improved milk fat precursors.
Butter Fat Yield Depressed 0.2–0.5%, lowering yield 5–15%. +0.132–0.331 lb/d fat gain. Higher milk value (+$0.61/hd/day).
Methane Production 10–20% higher emissions; energy wasted. −10–25% methane reduction. Eco-credits, greener footprint.
Feed Efficiency 5–12% lower efficiency, higher ration costs. +0.04–0.08 ECM/DMI. ~$0.63/hd/day savings on feed.

The Bottom Line

By targeting oxidative stress and unlocking the power of butyrate, Oxyntra delivers measurable health and performance benefits. Cows stay healthier, digest more efficiently, and produce more milk far, with lower methane output and higher profitability per head.

Science-backed. Field-proven. Oxyntra is redefining dairy nutrition for the modern herd. Reach out to our sales department to learn how to incorporate Oxyntra into your feeding strategy.

The next generation of dairy nutrition is here.

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